Article
Phospholipase A2 diversity and polymorphism in European viper venoms: paradoxical molecular evolution in Viperinae.
Toxicon : official journal of the International Society on Toxinology - 15 Dec 2007
Jan Virginie M, Guillemin Isabelle, Robbe-Vincent Annie, Choumet Valérie
Abstract excerpt
We report the diversity and polymorphism of phospholipase A(2) (PLA(2)) transcripts from snakes belonging to nine European viper subspecies. This diversity results in the expression of a combination of six PLA(2) species--ammodytin I1, ammodytin I2, ammodytin L, ammodytoxin, vaspin A and vaspin B--with 19 known isoforms of the first five of these species. Most of the European viper venoms studied contained either...
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