Article
Positive Darwinian selection in Vipera palaestinae phospholipase A2 genes is unexpectedly limited to the third exon.
Biochemical and biophysical research communications - 20 Oct 1998
Kordis D, Bdolah A, Gubensek F
Abstract excerpt
The venom of Vipera palaestinae contains a two-component toxin, consisting of an acidic phospholipase A2 (PLA2) and a basic protein. Here we report the cloning and sequence analysis of the complete V. palaestinae PLA2 genes. Since in all Viperidae PLA2 multigene families the 5' and 3' flanking re...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Conserved Sequence
- Crotalus
- Evolution, Molecular
- Exons
- Genetic Variation
- Humans
- Introns
- Molecular Sequence Data
- Multigene Family
- Phospholipases A
- Phospholipases A2
- Regulatory Sequences, Nucleic Acid
- Selection, Genetic
- Sequence Alignment
- Sequence Homology, Amino Acid