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Article

[Advance in research on the association of ALDH2 gene polymorphisms with cancer susceptibility in drinkers].

Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Feb 2015

Chen Chuanping, Li Luping

Abstract excerpt

Aldehyde dehydrogenase 2 (ALDH2), as one of the most important alcohol metabolizing enzymes, plays a significant role in the detoxification process of acetaldehyde which is a main carcinogenic product of alcoholic metabolism. Alteration in its genotypes (particularly at the site of rs671) is closely associated with a variety of tumors in drinkers. Recent advance in the research of the association of the ALDH2...

Topics

Alcohol Drinking
Aldehyde Dehydrogenase
Aldehyde Dehydrogenase, Mitochondrial
Genetic Predisposition to Disease
Humans
Neoplasms
Polymorphism, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25636114
DOI: 10.3760/cma.j.issn.1003-9406.2015.01.025

Genes

ALDH2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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