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Article

Clinical correlation of extensive-stage small-cell lung cancer genomics.

Annals of oncology : official journal of the European Society for Medical Oncology - 1 Apr 2016

Dowlati A, Lipka M B, McColl K, Dabir S, Behtaj M, Kresak A, Miron A, Yang M, Sharma N, Fu P, Wildey G

Abstract excerpt

BACKGROUND: Genomic studies in small-cell lung cancer (SCLC) lag far behind those carried out in nonsmall-cell lung cancer (NSCLC). To date, most SCLC studies have evaluated patients with surgically resectable disease. Here we sought to evaluate the genomic mutation spectrum of 'every-day' SCLC patient tumors with extensive stage disease (ES-SCLC) and to correlate mutations with the main clinical outcomes of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26802149
DOI: 10.1093/annonc/mdw005
PMCID: PMC4803453

Genes

FGFR1
KIT
PTCH1
RET
RICTOR

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