Article
Characteristics and prognosis of EGFR mutations in small cell lung cancer patients in the NGS era.
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico - 1 Feb 2024
Xie Xiaohong, Qiu Guihuan, Chen Ziyao, Liu Ting, Yang Yilin, You Zhixuan, Zeng Chen, Lin Xinqing, Xie Zhanhong, Qin Yinyin, Wang Yansheng, Ma Xiaodong, Zhou Chengzhi, Liu Ming
Abstract excerpt
PURPOSE: Targeted therapy has not been effective for small cell lung cancer (SCLC) patients. Although some studies have reported on EGFR mutations in SCLC, a systematic investigation into the clinical, immunohistochemical, and molecular characteristics and prognosis of EGFR-mutated SCLCs is lacking. METHODS: Fifty-seven SCLC patients underwent next-generation sequencing technology, with 11 in having EGFR...
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