Article
Relative Movements of Domains in Large Molecules of the Immune System.
Journal of immunology research - 1 Jan 2015
Schreiner Wolfgang, Karch Rudolf, Ribarics Reiner, Cibena Michael, Ilieva Nevena
Abstract excerpt
Molecular dynamics was used to simulate large molecules of the immune system (major histocompatibility complex class I, presented epitope, T-cell receptor, and a CD8 coreceptor.) To characterize the relative orientation and movements of domains local coordinate systems (based on principal component analysis) were generated and directional cosines and Euler angles were computed. As a most interesting result, we...
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