Article

Dimensionality Reduction-Based Analysis of the Molecular Dynamics of G Protein-Coupled Receptors

2024-03-12

Abstract excerpt

G-protein coupled receptors (GPCRs) are the most abundant and varied family of transmembrane proteins. Beyond their basic biological functions, they are of relevance to pharmacology, as they are involved in a variety of human pathologies. Molecular dynamics (MD) are a reliable and effective simulation technique that allows us to investigate and examine the structure and activity that shape biomolecular energy syst...

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Literature Corpus work: 60343970-d02d-5758-9cb9-7bd59fcd099e
DOI: 10.22541/au.171026627.78764691/v1

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