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Article

Effects of disease causing mutations on the essential motions in proteins.

Journal of biomolecular structure & dynamics - 1 Apr 2009

Achary Malkaram S, Nagarajaram Hampapathalu A

Abstract excerpt

This study embodies a detailed comparative analysis of the essential motions of the Wild type and the eight different disease mutant forms of the Human CYP1b1. The mutations considered in this study have been implicated in Primary Congenital Glaucoma, an in-born, genetic disorder associated with eye-abnormality. The principal component analysis for Wild type and the Mutants was carried out using the stabilized...

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Share to Aryl Hydrocarbon Hydroxylases
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19236111
DOI: 10.1080/07391102.2009.10507276

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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