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Hydrogen peroxide-mediated induction of the Shiga toxinconverting lambdoid prophage ST2-8624 inEscherichia coliO157:H7

12 Jan 2010

Abstract excerpt

Shiga toxin-producing Escherichia coli (STEC) may cause bloody diarrhea and hemorrhagic colitis, with sometimes severe complications. Because genes coding for Shiga toxins are located on lambdoid prophages, effective toxin production occurs only after prophage induction. However, although agents that effectively induce prophage lambda (a paradigm of the family of lambdoid phages) under laboratory conditions, such...

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PMID: 20070366
DOI: 10.1111/j.1574-695x.2009.00644.x

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