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Article

The stimulatory effects of eNOS/F92A-Cav1 on NO production and angiogenesis in BMSCs.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie - 1 Feb 2016

Xia Peng, Chen Hai-Ying, Chen Shuang-Feng, Wang Lei, Strappe Pádraig Michael, Yang Hong-Li, Zhou Chang-Hui, Zhang Xiao, Zhang Ying-Xin, Ma Long-le, Wang Lexin

Abstract excerpt

BACKGROUND: Nitric oxide (NO) is generated in endothelial cells by endothelial nitric oxide synthase (eNOS). Caveolin-1 (Cav1) inhibits eNOS function and NO production. Modifying Cav1 scaffold domain, in particular Phenylalanine at position 92 (F92) is critical for the inhibitory actions of Cav1 toward eNOS. The aims of this study were to investigate the effect of enhanced NO production in term of in vitro...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26796258
DOI: 10.1016/j.biopha.2015.11.001

Genes

CCK
PAH

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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