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Article

eNOS transfection of adipose-derived stem cells yields bioactive nitric oxide production and improved results in vascular tissue engineering.

Journal of tissue engineering and regenerative medicine - 1 Nov 2015

McIlhenny Stephen, Zhang Ping, Tulenko Thomas, Comeau Jason, Fernandez Sarah, Policha Aleksandra, Ferroni Matthew, Faul Elizabeth, Bagameri Gabor, Shapiro Irving, DiMuzio Paul

Abstract excerpt

This study evaluates the durability of a novel tissue engineered blood vessel (TEBV) created by seeding a natural vascular tissue scaffold (decellularized human saphenous vein allograft) with autologous adipose-derived stem cells (ASC) differentiated into endothelial-like cells. Previous work with this model revealed the graft to be thrombogenic, likely due to inadequate endothelial differentiation as evidenced...

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Source

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Identifiers

PMID: 23319464
DOI: 10.1002/term.1645
PMCID: PMC4050122

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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