Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A conditionally lethal mutant of Salmonella Typhimurium induces a protective response in mice.

Biochemical and biophysical research communications - 5 Feb 2016

Hidalgo Alejandro A, Villagra Nicolás A, Jerez Sebastián A, Fuentes Juan A, Mora Guido C

Abstract excerpt

Here we present the design of a conditionally lethal mutant of Salmonella enterica serovar Typhimurium (S. Typhimurium) which growth depends on tetracycline (Tet). Four mutants of S. Typhimurium, with Tet-conditional growth, were created by inserting the tetRA cassette. Three of the mutants presented a conditional-lethal phenotype in vitro. One mutant in the yabB gene remained conditional inside cells and did not...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Administration, Oral
Share to Bacterial Vaccines

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mice, Inbred BALB C

Share to Mutation

Share to Salmonella Infections

Share to Salmonella typhimurium

Share to Species Specificity

Source

Identifiers

PMID: 26792728
DOI: 10.1016/j.bbrc.2016.01.058

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A conditionally lethal mutant of Salmonella Typhimurium induces a protective response in mice.PMID 26792728Read ↗

The putative iron transport system SitABCD encoded on SPI1 is required for full virulence of Salmonella typhimurium.Semantic proximity Read ↗

Protective capacity of a temperature-sensitive mutant of Salmonella enteritidis after oral and intragastric inoculation in a murine model.Semantic proximity Read ↗

Genetically stable temperature-sensitive mutants of Salmonella typhi induce protection in mice.Semantic proximity Read ↗

Identification of genes that are dispensable for animal infection by Salmonella typhimurium.Semantic proximity Read ↗

Salmonella enteritidis has a homologue of tolC that is required for virulence in BALB/c mice.Semantic proximity Read ↗

Salmonella typhimurium encodes a putative iron transport system within the centisome 63 pathogenicity island.Semantic proximity Read ↗

Protection and immune responses induced by attenuated Salmonella typhimurium UK-1 strains.Semantic proximity Read ↗

Intestinal invasion of Salmonella enterica serovar Typhimurium in the avian host is dose dependent and does not depend on motility and chemotaxis.Semantic proximity Read ↗

Characterization of a highly attenuated Salmonella enterica serovar Typhimurium mutant strain.Semantic proximity Read ↗

At least four percent of the Salmonella typhimurium genome is required for fatal infection of mice.Semantic proximity Read ↗

Triclosan resistance in Salmonella enterica serovar Typhimurium.Semantic proximity Read ↗

Salmonella typhimurium thyA mutants fail to grow intracellularly in vitro and are attenuated in mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.