Article
The putative iron transport system SitABCD encoded on SPI1 is required for full virulence of Salmonella typhimurium.
Molecular microbiology - 1 Mar 2000
Janakiraman A, Slauch J M
Abstract excerpt
Salmonella typhimurium is an invasive pathogen that causes diseases ranging from mild gastroenteritis to enteric fever. During the infection process, S. typhimurium induces a number of virulence genes required to circumvent host defences and/or acquire nutrients in the host. We have used the in vivo expression technology (IVET) system to select for S. typhimurium genes that are induced after invasion of a murine...
Topics
- Animals
- Biological Transport
- Carrier Proteins
- Genes, Bacterial
- Iron
- Mice
- Mice, Inbred BALB C
- Mice, Inbred C3H
- Mutation
- Operon
- Salmonella Infections
- Salmonella typhimurium