Article
Triclosan resistance in Salmonella enterica serovar Typhimurium.
The Journal of antimicrobial chemotherapy - 1 Jul 2008
Webber Mark A, Randall Luke P, Cooles Susan, Woodward Martin J, Piddock Laura J V
Abstract excerpt
OBJECTIVES: The aim of this study was to characterize the mechanisms of resistance to triclosan in Salmonella enterica serovar Typhimurium. METHODS: Mutants resistant to triclosan were selected from nine S. enterica serovar Typhimurium strains. Mutants were characterized by genotyping, mutagenesis and complementation of fabI and analysis of efflux activity. Fitness of triclosan-resistant mutants was determined in...
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