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Article

TPM1 polymorphisms and nonsyndromic orofacial clefts susceptibility in a Chinese Han population.

American journal of medical genetics. Part A - 1 May 2016

Qian Yajing, Li Dandan, Ma Lan, Zhang Hongchuang, Gong Miao, Li Sheng, Yuan Hua, Zhang Weibing, Ma Junqing, Jiang Hongbing, Pan Yongchu, Wang Lin

Abstract excerpt

Located at 15q22 a susceptibility region for nonsyndromic orofacial clefts (NSOC), TPM1 encodes a group of highly conserved ubiquitous actin-binding proteins involved in the muscle contraction and cytoskeleton organization. Considering the multiple functions of TPM1 gene, we investigated the potential relationship between TPM1 polymorphisms and risk of NSOC in a Chinese Han population. Four tag single nucleotide...

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Source

Identifiers

PMID: 26792422
DOI: 10.1002/ajmg.a.37561

Genes

TPM1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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