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Article

Association between PAX7 and NTN1 gene polymorphisms and nonsyndromic orofacial clefts in a northern Chinese population.

Medicine - 1 May 2017

Guo Qiang, Li Dongmei, Meng Xiangbiao, Liu Tingting, Shi Jinna, Hao Yanru, Jiao Xiaohui, Lv Kewen, Hu Tenglong, Song Tao

Abstract excerpt

BACKGROUND: Nonsyndromic orofacial clefts (NSOC) are the most common orofacial congenital defect with a complex etiology. Genome-wide association studies have identified paired box protein 7 (PAX7) and netrin-1 (NTN1) as candidate susceptibility genes for NSOC in both European and Asian populations. Here, possible associations between single-nucleotide polymorphisms (SNPs) in or near PAX7 and NTN1 were...

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Source

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Identifiers

PMID: 28489749
DOI: 10.1097/MD.0000000000006724
PMCID: PMC5428583

Genes

NTN1
PAX7

Provenance

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