Article
Functional Effects of SNPs in MYH9 and Risks of Nonsyndromic Orofacial Clefts.
Journal of dental research - 1 Apr 2018
Wang Y, Li D, Xu Y, Ma L, Lu Y, Wang Z, Wang L, Zhang W, Pan Y
Abstract excerpt
Nonsyndromic orofacial clefts (NSOCs) are congenital newborn malformations. Myosin heavy chain 9 ( MYH9) is a candidate gene of NSOCs. To investigate the associations between single-nucleotide polymorphisms (SNPs) of MYH9 and NSOC susceptibility, a 2-stage case-control study was designed and 4 potentially functional SNPs of MYH9 (rs12107, rs2269529, rs9619601, rs5756130) were selected and genotyped by iPLEX...
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