Article
ApoE4 and late onset depression in Indian population.
Journal of affective disorders - 1 Feb 2012
Sureshkumar R, Bharath S, Jain S, Prakash O, Purushottam M, Thennarasu K, Mukherjee O, Sivakumar P T, Varghese M
Abstract excerpt
OBJECTIVE: ApoE4 is a 'risk factor' for cognitive disorders like Alzheimer's dementia, and Late Onset Depression (LOD) is a forerunner of dementia. There is thus a need to study the association between ApoE4 allele and LOD. METHOD: The study assessed the frequency of ApoE4 allele in 31 cases of LOD above the age of 50 years and 31 matched controls. The subjects were assessed on various clinical parameters towards...
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