Article
No association between APOE and major depressive disorder in a community sample of 17,507 adults.
Journal of psychiatric research - 1 Jun 2009
Surtees Paul G, Wainwright Nicholas W J, Bowman Richard, Luben Robert N, Wareham Nicholas J, Khaw Kay-Tee, Bingham Sheila A
Abstract excerpt
Mood-related phenotypes are commonly comorbid with, and have been implicated in the development of, neurological disorders. APOE is a major susceptibility gene for neurodegeneration. Recent evidence from case-control studies has suggested that the apoE 2 allele is associated with major depressive disorder (MDD). However, evidence from large-scale community-based studies is limited. APOE was genotyped for 17,507...
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