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Article

A longitudinal study of apolipoprotein-E genotype and depressive symptoms in community-dwelling older adults.

The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry - 1 Jan 2000

Mauricio M, O'Hara R, Yesavage J A, Friedman L, Kraemer H C, Van De Water M, Murphy G M

Abstract excerpt

The Apolipoprotein-E (APOE) epsilon 4 allele is a risk factor for Alzheimer's disease (AD) and cognitive decline in older adults. Depression may also be a risk factor for dementia, and depression is important in the differential diagnosis of dementia. The authors performed a 5-year longitudinal study of APOE genotype and change in Geriatric Depression Scale scores in 113 community-dwelling older adults. No...

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Source

Identifiers

PMID: 10910416

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A longitudinal study of apolipoprotein-E genotype and depressive symptoms in community-dwelling older adults.PMID 10910416Read ↗

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Apolipoprotein E genotype in the prediction of cognitive decline and dementia in a prospectively studied elderly population.Semantic proximity Read ↗

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Depressive symptoms moderate the influence of the apolipoproteine epsilon4 allele on cognitive decline in a sample of community dwelling older adults.Semantic proximity Read ↗

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