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Article

Expression profiles of MMP-1 and TIMP-1 in lumbar intervertebral disc degeneration.

Genetics and molecular research : GMR - 29 Dec 2015

Deng B, Ren J Z, Meng X Q, Pang C G, Duan G Q, Zhang J X, Zou H, Yang H Z, Ji J J

Abstract excerpt

Lumbar intervertebral disc degeneration (IDD) is a common clinical pathology and has become a focus for research in recent years. Matrix metalloproteinases (MMPs) are enzymes responsible for the degradation of almost all extracellular matrix proteins (ECM). The over-expression of MMPs or tissue inhibitors of metalloproteinases (TIMPs) may disrupt the dynamic balance of the ECM. Therefore, in the current study,...

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Identifiers

PMID: 26782559
DOI: 10.4238/2015.December.29.16

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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