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Article

Role of hypoxia and interleukin-1beta in gene expressions of matrix metalloproteinases in temporomandibular joint disc cells.

Archives of oral biology - 1 Jan 2005

Yamaguchi Akihiko, Tojyo Itaru, Yoshida Hiroaki, Fujita Shigeyuki

Abstract excerpt

The aim of this study was to test the hypothesis that hypoxia and interleukin-1 (IL-1)beta played a substantial role in gene expressions of matrix metalloproteinases (MMPs) in temporomandibular joint (TMJ) disc cells. The TMJ disc cells were isolated from rabbit TMJ, and cultured in Dulbecco's modified Eagle's medium (DMEM). The experiment was performed for 24 h in hypoxic (2% O2) and IL-1beta stimulated...

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Identifiers

PMID: 15598420
DOI: 10.1016/j.archoralbio.2004.06.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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