Article
[Relationship between 666C > T polymorphism of TIMP-1 and lumbar intervertebral disc degeneration].
Zhonghua yi xue za zhi - 9 Nov 2010
Xiao Bin, Tian Wei, Zhao Dan-hui, Wu Cheng-ai, Wang Na, Zhang Yan-zhuo
Abstract excerpt
OBJECTIVE: To detect the single nucleotide polymorphisms (SNPs) in exon 6 of tissue inhibitor of metalloproteinase-1 (TIMP-1) in young men in North China and to investigate the relationship between these polymorphisms and lumbar intervertebral disc degeneration. METHODS: The recruited subjects aged from 18 to 40 years old were divided by MRI into degeneration group (n = 48) and non-degeneration group (n = 49)....
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