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The mechanisms and functions of IL-1β in intervertebral disc degeneration

24 Apr 2023

Abstract excerpt

Intervertebral disc degeneration (IDD) is the leading cause of low back pain (LBP) and disability in the elderly, imposing significant public health and economic burden worldwide. Meanwhile, the pathological mechanisms of IDD remain complicated, and treatment strategy to reverse IDD is primarily due to the unclear specific mechanisms of IDD and the lack of particular effective targets. Interleukin-1β (IL-1β), one...

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PMID: 37088216
DOI: 10.1016/j.exger.2023.112181

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