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The role of IL-1β and TNF-α in intervertebral disc degeneration

24 Aug 2020

Abstract excerpt

Low back pain (LBP), a prevalent and costly disease around the world, is predominantly caused by intervertebral disc (IVD) degeneration (IDD). LBP also presents a substantial burden to public health and the economy. IDD is mainly caused by aging, trauma, genetic susceptibility, and other factors. It is closely associated with changes in tissue structure and function, including progressive destruction of the...

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PMID: 32853910
DOI: 10.1016/j.biopha.2020.110660

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