Article
Genomic Biomarkers for the Prediction of Stage and Prognosis of Upper Tract Urothelial Carcinoma.
The Journal of urology - 1 Jun 2016
Bagrodia Aditya, Cha Eugene K, Sfakianos John P, Zabor Emily C, Bochner Bernard H, Al-Ahmadie Hikmat A, Solit David B, Coleman Jonathan A, Iyer Gopa, Scott Sasinya N, Shah Ronak, Ostrovnaya Irina, Lee Byron, Desai Neil B, Ren Qinghu, Rosenberg Jonathan E, Dalbagni Guido, Bajorin Dean F, Reuter Victor E, Berger Michael F
Abstract excerpt
PURPOSE: Genomic characterization of radical nephroureterectomy specimens in patients with upper tract urothelial carcinoma may allow for thoughtful integration of systemic and targeted therapies. We sought to determine whether genomic alterations in upper tract urothelial carcinoma are associated with adverse pathological and clinical outcomes. MATERIALS AND METHODS: Next generation exon capture sequencing of...
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