Retrospective Multicenter Study Investigating the Role of Targeted Next-Generation Sequencing of Selected Cancer Genes in Mucinous Adenocarcinoma of the Lung.

doi:10.1016/j.jtho.2016.01.004

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Article

Retrospective Multicenter Study Investigating the Role of Targeted Next-Generation Sequencing of Selected Cancer Genes in Mucinous Adenocarcinoma of the Lung.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Apr 2016

Righi Luisella, Vatrano Simona, Di Nicolantonio Federica, Massa Federica, Rossi Giulio, Cavazza Alberto, Volante Marco, Votta Arianna, Izzo Stefania, Lo Iacono Marco, Ardissone Francesco, Di Maio Massimo, Novello Silvia, Scagliotti Giorgio Vittorio, Papotti Mauro

Abstract excerpt

INTRODUCTION: Mucin-rich lung adenocarcinomas (ADCs), namely mucinous and colloid ADCs, are classified as ADC variants according to the World Health Organization 2015 classification. A correlation between morphological patterns and mutational status of these rare entities is not well established. METHODS: We investigated the mutational profile of mucin-rich lung ADCs in correlation with histopathological and...

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PMID: 26774193
DOI: 10.1016/j.jtho.2016.01.004

Genes

EGFR
KRAS

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