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Article

Mutational analysis of pulmonary tumours with neuroendocrine features using targeted massive parallel sequencing: a comparison of a neglected tumour group.

British journal of cancer - 22 Dec 2015

Vollbrecht Claudia, Werner Robert, Walter Robert Fred Henry, Christoph Daniel Christian, Heukamp Lukas Carl, Peifer Martin, Hirsch Burkhard, Burbat Lina, Mairinger Thomas, Schmid Kurt Werner, Wohlschlaeger Jeremias, Mairinger Fabian Dominik

Abstract excerpt

BACKGROUND: Lung cancer is the leading cause of cancer-related deaths worldwide. The typical and atypical carcinoid (TC and AC), the large-cell neuroendocrine carcinoma (LCNEC) and the small-cell lung cancers (SCLC) are subgroups of pulmonary tumours that show neuroendocrine differentiations. With the rising impact of molecular pathology in routine diagnostics the interest for reliable biomarkers, which can help...

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Identifiers

PMID: 26645239
DOI: 10.1038/bjc.2015.397
PMCID: PMC4701994

Genes

ATM
APC
FGFR2
JAK3
KIT
NRAS
PTEN
SMAD4
SMO

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Source receipt: pubmed, retrieved 7 Sept 2026.

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