Article
Cyclophosphamide pharmacokinetics and pharmacogenetics in children with B-cell non-Hodgkin's lymphoma.
European journal of cancer (Oxford, England : 1990) - 1 Mar 2016
Veal Gareth J, Cole Michael, Chinnaswamy Girish, Sludden Julieann, Jamieson David, Errington Julie, Malik Ghada, Hill Christopher R, Chamberlain Thomas, Boddy Alan V
Abstract excerpt
INTRODUCTION: Variation in cyclophosphamide pharmacokinetics and metabolism has been highlighted as a factor that may impact on clinical outcome in various tumour types. The current study in children with B-cell non-Hodgkin's lymphoma (NHL) was designed to corroborate previous findings in a large prospective study incorporating genotype for common polymorphisms known to influence cyclophosphamide pharmacology....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
