Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Neuroprotective effects of bee venom phospholipase A2 in the 3xTg AD mouse model of Alzheimer's disease.

Journal of neuroinflammation - 16 Jan 2016

Ye Minsook, Chung Hwan-Suck, Lee Chanju, Yoon Moon Sik, Yu A Ram, Kim Jin Su, Hwang Deok-Sang, Shim Insop, Bae Hyunsu

Abstract excerpt

BACKGROUND: Alzheimer's disease (AD) is a severe neuroinflammatory disease. CD4(+)Foxp3(+) regulatory T cells (Tregs) modulate various inflammatory diseases via suppressing Th cell activation. There are increasing evidences that Tregs have beneficial roles in neurodegenerative diseases. Previously, we found the population of Treg cells was significantly increased by bee venom phospholipase A2 (bvPLA2) treatment...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Escape Reaction
Share to Fluorodeoxyglucose F18

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Learning Disabilities

Share to Maze Learning

Share to Neuroprotective Agents

Share to Phospholipases A2

Share to Radionuclide Imaging

Share to T-Lymphocytes, Regulatory

Source

Open in PubMed Open full text

Identifiers

PMID: 26772975
DOI: 10.1186/s12974-016-0476-z
PMCID: PMC4715334

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Neuroprotective effects of bee venom phospholipase A2 in the 3xTg AD mouse model of Alzheimer's disease.PMID 26772975Read ↗

Glial cell transcriptome analyses in 3xTg-AD mice: Effects of aging, disease progression, and anti-Aβ immunotherapySemantic proximity Read ↗

Ex vivo Expanded Human Regulatory T Cells Modify Neuroinflammation in a Preclinical Model of Alzheimer’s diseaseSemantic proximity Read ↗

Isobavachalcone ameliorates Alzheimer disease pathology by autophagy-mediated clearance of amyloid beta and inhibition of NLRP3 inflammasome in 5XFAD miceSemantic proximity Read ↗

A preclinical and phase I clinical study of ex vivo-expanded amyloid beta-specific human regulatory T cells in Alzheimer’s diseaseSemantic proximity Read ↗

Guizhi Fuling capsule relieves memory deficits by inhibition of microglial neuroinflammation through blocking JAK2/STAT3 pathway in presenilin1/2 conditional double knockout miceSemantic proximity Read ↗

Blockage of CCL3 with neutralizing antibody reduces neuroinflammation and reverses Alzheimer disease phenotypesSemantic proximity Read ↗

Glibenclamide modulates microglial function and attenuates Aβ deposition in 5XFAD mice.Semantic proximity Read ↗

Protective effects of CCL01 against Aβ-induced neurotoxicity in 5xFAD transgenic mouse model of Alzheimer's diseaseSemantic proximity Read ↗

Tβ4 and PDTC displayed recovery on the glial and neuronal alterations in an early Alzheimer’s disease modelSemantic proximity Read ↗

K284-6111 Alleviates Memory Impairment and Neuroinflammation in Tg2576 Mice by Inhibition of Chitinase-3-like 1 Regulating ERK Dependent PTX3 PathwaySemantic proximity Read ↗

Peripheral blood lymphocyte phenotypes in Alzheimer and Parkinson's diseases.Semantic proximity Read ↗

Therapeutic B-cell depletion reverses progression of Alzheimer's disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.