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Article

A germline predictive signature of response to platinum chemotherapy in esophageal cancer.

Translational research : the journal of laboratory and clinical medicine - 1 May 2016

Rumiato Enrica, Boldrin Elisa, Malacrida Sandro, Battaglia Giorgio, Bocus Paolo, Castoro Carlo, Cagol Matteo, Chiarion-Sileni Vanna, Ruol Alberto, Amadori Alberto, Saggioro Daniela

Abstract excerpt

Platinum-based neoadjuvant therapy is the standard treatment for esophageal cancer (EC). At present, no reliable response markers exist, and patient therapeutic outcome is variable and very often unpredictable. The aim of this study was to understand the contribution of host constitutive DNA polymorphisms in discriminating between responder and nonresponder patients. DNA collected from 120 EC patients treated...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26772957
DOI: 10.1016/j.trsl.2015.12.011

Genes

ABCC2
ABCC3
ERCC1
PPARG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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