Article
beta2-adrenoceptor genotype affects vasopressor requirements during spinal anesthesia for cesarean delivery.
Anesthesiology - 1 Apr 2006
Smiley Richard M, Blouin Jean-Louis, Negron Maria, Landau Ruth
Abstract excerpt
BACKGROUND: Maternal hypotension is common after spinal anesthesia for cesarean delivery. There is wide variability in the incidence and severity of hypotension and in the response to treatment. The beta2 adrenoceptor (beta2AR) possesses several polymorphic sites. Codons 16 (Arg16Gly) and 27 (Glu27Gln) have been shown to affect desensitization of the receptor. The goal of this study was to determine whether...
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