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Article

Lysosomal alterations in peripheral blood mononuclear cells of Parkinson's disease patients.

Movement disorders : official journal of the Movement Disorder Society - 1 Nov 2015

Papagiannakis Nikolaos, Xilouri Maria, Koros Christos, Stamelou Maria, Antonelou Roubina, Maniati Matina, Papadimitriou Dimitra, Moraitou Marina, Michelakakis Helen, Stefanis Leonidas

Abstract excerpt

BACKGROUND: Reduced expression of lysosomal-associated membrane protein 2a and heatshock-cognate 70 proteins, involved in chaperone-mediated autophagy and of glucocerebrosidase, is reported in PD brains. The aim of this study was to identify systemic alterations in lysosomal-associated membrane protein 2a, heatshock cognate-70, and glucocerebrosidase levels/activity in peripheral blood mononuclear cells from PD...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26769460
DOI: 10.1002/mds.26433

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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