Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Role of Chaperone-Mediated Autophagy Dysfunctions in the Pathogenesis of Parkinson’s Disease

23 Dec 2016

Abstract excerpt

Chaperone-mediated autophagy (CMA) represents a selective form of autophagy involved in the degradation of specific soluble proteins containing a pentapeptide motif that is recognized by a cytosolic chaperone able to deliver proteins to the lysosomes for degradation. Physiologically, CMA contributes to maintain crucial cellular functions including energetic balance and protein quality control. Dysfunctions in CMA...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy in Disease and Therapy
Share to Endoplasmic Reticulum Stress and Disease
Share to Parkinson's Disease Mechanisms and Treatments

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28066181
DOI: 10.3389/fnmol.2016.00157

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 20 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Role of Chaperone-Mediated Autophagy Dysfunctions in the Pathogenesis of Parkinson’s DiseasePMID 28066181Read ↗

Chaperone-mediated autophagy as a therapeutic target for Parkinson diseaseSemantic proximity Read ↗

Chaperone-mediated autophagy: roles in neurodegenerationSemantic proximity Read ↗

Chaperone-Mediated Autophagy and Its Implications for Neurodegeneration and CancerSemantic proximity Read ↗

Dysregulation of autophagy and mitochondrial function in Parkinson’s diseaseSemantic proximity Read ↗

Role of Autophagy in Parkinson's Disease.Semantic proximity Read ↗

Autophagy in Parkinson's DiseaseSemantic proximity Read ↗

Autophagy-Lysosomal Pathway as Potential Therapeutic Target in Parkinson's Disease.Semantic proximity Read ↗

Autophagy deregulation in neurodegenerative diseases – recent advances and future perspectivesSemantic proximity Read ↗

Autophagy in Neurodegenerative Diseases: A Hunter for AggregatesSemantic proximity Read ↗

Autophagy in neurodegenerative diseases: pathogenesis and therapySemantic proximity Read ↗

Advances in autophagy for Parkinson’s disease pathogenesis and treatmentSemantic proximity Read ↗

Targeting chaperone-mediated autophagy in neurodegenerative diseases: mechanisms and therapeutic potentialSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.