Article
Rab GTPases, membrane trafficking and diseases.
Current drug targets - 1 Jul 2011
Li Guangpu
Abstract excerpt
The Rab family of GTPases contains over 60 genes in the human genome and contributes to regulation of intracellular membrane trafficking along endocytic and exocytic pathways as well as specialized pathways in specific cell types. It has become increasingly clear that disruption of the intracellular membrane trafficking system at different stages can cause various diseases. In the past decade, altered expression...
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