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Article

Maturation and electrophysiological properties of human pluripotent stem cell-derived oligodendrocytes.

Stem cells (Dayton, Ohio) - 1 Apr 2016

Livesey Matthew R, Magnani Dario, Cleary Elaine M, Vasistha Navneet A, James Owain T, Selvaraj Bhuvaneish T, Burr Karen, Story David, Shaw Christopher E, Kind Peter C, Hardingham Giles E, Wyllie David J A, Chandran Siddharthan

Abstract excerpt

Rodent-based studies have shown that the membrane properties of oligodendrocytes play prominent roles in their physiology and shift markedly during their maturation from the oligodendrocyte precursor cell (OPC) stage. However, the conservation of these properties and maturation processes in human oligodendrocytes remains unknown, despite their dysfunction being implicated in human neurodegenerative diseases such...

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Identifiers

PMID: 26763608
DOI: 10.1002/stem.2273
PMCID: PMC4840312

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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