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Article

Quantitative genetics of circulating Dickkopf-related protein 1 (DKK1) in community-based sample of UK twins.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA - 1 Jun 2016

Prakash J, Williams F M K, Trofimov S, Surdulescu G, Spector T, Livshits G

Abstract excerpt

UNLABELLED: Dickkopf-related protein 1 (DKK1) is a major inhibitor of Wnt signalling pathway but also plays an important role in bone formation. Its circulating levels appear to correlate significantly with plasma levels of inflammatory factors, fractalkine and IL-6. This study, using a large sample of UK twins, showed that the variation of each of these factors and correlation between them was explained by the...

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Source

Identifiers

PMID: 26762129
DOI: 10.1007/s00198-016-3486-x

Genes

DKK1
MAF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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