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Article

Investigating the causal effect of Dickkopf-1 on coronary artery disease and ischemic stroke: a Mendelian randomization study.

Aging - 22 Sept 2023

Zheng Peng-Fei, Rong Jing-Jing, Zheng Zhao-Fen, Liu Zheng-Yu, Pan Hong-Wei, Liu Peng

Abstract excerpt

Epidemiological investigations have indicated a correlation between elevated plasma levels of Dickkopf-related protein 1 (DKK1) and the presence of atherosclerosis. However, the exact causal relationship of DKK1 with the development of coronary artery disease (CAD) and ischemic stroke (IS) remains unclear. To address this gap, our study aimed to explore their causal association using a two-sample Mendelian...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 37742224
DOI: 10.18632/aging.205050
PMCID: PMC10564415

Genes

DKK1
CAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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