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Article

Genetic association study of Dickkopf-1 and sclerostin genes with paget disease of bone.

Calcified tissue international - 1 Nov 2013

Beauregard Mariejka, Gagnon Edith, Guay-Bélanger Sabrina, Siris Ethel S, Morissette Jean, Brown Jacques P, Michou Laëtitia

Abstract excerpt

Increased expression of DKK1 gene was reported in pagetic osteoblasts and stromal cells, and increased serum levels of DKK1 and SOST proteins were reported in patients with Paget disease of bone (PDB). This study aimed at identifying rare genetic variants of the DKK1 and SOST genes and at testing for genetic association with PDB in the French-Canadian population. Exons, promoters, and exon-intron junctions of...

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Source

Identifiers

PMID: 23836157
DOI: 10.1007/s00223-013-9762-2

Genes

DKK1
SOST

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genetic association study of Dickkopf-1 and sclerostin genes with paget disease of bone.PMID 23836157Read ↗

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