Article
Circulating Myeloid-Derived Suppressor Cells Predict Differentiated Thyroid Cancer Diagnosis and Extent.
Thyroid : official journal of the American Thyroid Association - 1 Mar 2016
Angell Trevor E, Lechner Melissa G, Smith Alison M, Martin Sue E, Groshen Susan G, Maceri Dennis R, Singer Peter A, Epstein Alan L
Abstract excerpt
BACKGROUND: Establishing the preoperative diagnosis and long-term prognosis of differentiated thyroid cancer (DTC) remain challenging in some patients. Myeloid-derived suppressor cells (MDSC) are tumor-induced cells mediating immune tolerance that are detectable in the peripheral blood of cancer patients. The authors previously developed a novel clinical assay to detect the phenotypes of two human MDSC subsets in...
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