Article

BRAF <sup>V600E</sup> expression in thyrocytes causes recruitment of immunosuppressive STABILIN-1 macrophages

2022-07-29

Abstract excerpt

Papillary thyroid carcinoma (PTC) is the most frequent histological subtype of thyroid cancers (TC), and BRAF V600E genetic alteration is found in 60% of this endocrine cancer. This oncogene is associated with poor prognosis, resistance to radioiodine therapy and tumor progression. Histological follow-up by anatomo-pathologists reveals that 2/3 of surgically-removed thyroids do not present malignant lesions. Cont...

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Literature Corpus work: 80807763-4777-5d1d-838d-5e14d2ab0625
DOI: 10.1101/2022.07.27.501733

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