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IS MEASUREMENT OF CIRCULATING TUMOR DNA OF DIAGNOSTIC USE IN PATIENTS WITH THYROID NODULES?

Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists - 1 May 2018

Lupo Mark, Guttler Richard, Geck Zsofia, Tonozzi Theresa R, Kammesheidt Anja, Braunstein Glenn D

Abstract excerpt

OBJECTIVE: Circulating tumor DNA (ctDNA), a subset of cell-free DNA (cfDNA), is a potential biomarker for thyroid cancer. We determined the performance of a ctDNA panel for detecting thyroid malignancy in patients with thyroid nodules. METHODS: Sixty-six patients with thyroid nodules without a prior history of cancer enrolled in a prospective, 1-year study in which blood was drawn for ctDNA analysis prior to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 29498908
DOI: 10.4158/EP-2017-0213

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KRAS

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