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Article

Renin gene rs1464816 polymorphism contributes to chronic kidney disease progression in ADPKD.

Journal of biomedical science - 11 Jan 2016

Ramanathan Gnanasambandan, Elumalai Ramprasad, Periyasamy Soundararajan, Lakkakula Bhaskar V K S

Abstract excerpt

BACKGROUND: Autosomal dominant polycystic kidney disease (ADPKD) is a monogenic disorder and is a common genetic cause of chronic renal failure in children and adults. The enzyme renin plays a key role in the RAAS cascade and an important role in the development of hypertension and progression of renal disease in ADPKD. The present study is aimed to investigate the potential modifier effect of REN gene...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26753721
DOI: 10.1186/s12929-015-0217-0
PMCID: PMC4710007

Genes

REN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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