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Article

Renin-Angiotensin-Aldosterone System Antagonism and Polycystic Kidney Disease Progression.

Nephron - 1 Jan 2016

Hian Chuan Kai, Lee Chin Liang, Thomas Warren

Abstract excerpt

Autosomal Dominant Polycystic Kidney Disease (ADPKD) is a systemic disease characterised by the formation of multiple renal cysts that adversely affect renal function. ADPKD shows significant progression with age when complications due to hypertension are most significant. The activation of the renin-angiotensin-aldosterone system (RAAS) occurs in progressive kidney disease leading to hypertension. The RAAS...

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PMID: 27476173
DOI: 10.1159/000448296

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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