Article
Angiotensinogen gene polymorphisms and progression of chronic kidney disease in ADPKD patients.
Clinical and experimental nephrology - 1 Aug 2016
Gnanasambandan Ramanathan, Elumalai Ramprasad, Soundararajan Periyasamy, Lakkakula Bhaskar V K S
Abstract excerpt
BACKGROUND: Autosomal dominant polycystic kidney disease (ADPKD) is a multisystemic and progressive disorder characterized by cyst formation and kidney enlargement and ultimately renal failure. Reduction of CKD progression in the ADPKD by pharmacological blockade of the renin-angiotensin-aldosterone system (RAAS) using ACE inhibitors indicated the involvement of RAAS pathway in the progression of CKD. The aim of...
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