Article
NOS3 tagSNPs does not modify the chronic kidney disease progression in autosomal dominant polycystic kidney disease.
Nephrology (Carlton, Vic.) - 1 Sept 2014
Ramanathan Gnanasambandan, Periyasamy Soundararajan, Lakkakula Bhaskar Vks
Abstract excerpt
AIM: Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary and progressive renal disorder. It is also recognised as the most frequent genetic cause of chronic kidney diseases (CKD). In the present study, four tagging SNPs and two more well studied polymorphisms (Intron 4 VNTR and Glu298Asp) the NOS3 gene were investigated to unravel the potential modifier effect of NOS3 gene on the...
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