Article
Influence of angiotensin converting enzyme (ACE) gene rs4362 polymorphism on the progression of kidney failure in patients with autosomal dominant polycystic kidney disease (ADPKD).
The Indian journal of medical research - 1 Jun 2016
Ramanathan Gnanasambandan, Ghosh Santu, Elumalai Ramprasad, Periyasamy Soundararajan, Lakkakula Bhaskar V K S
Abstract excerpt
BACKGROUND & OBJECTIVES: Autosomal dominant polycystic kidney disease (ADPKD) is an inherited systemic disorder, characterized by the fluid filled cysts in the kidneys leading to end stage renal failure in later years of life. Hypertension is one of the major factors independently contributing to the chronic kidney disease (CKD) progression. The renin-angiotensin aldosterone system (RAAS) genes have been...
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