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Article

Influence of the alpha-adducin and ACE gene polymorphism on the progression of autosomal-dominant polycystic kidney disease.

Kidney & blood pressure research - 1 Jan 2003

Merta M, Reiterová J, Stekrová J, Rysava R, Rihová Z, Tesar V, Viklický O, Kmentova D

Abstract excerpt

BACKGROUND: A significant phenotypical variability is observed in autosomal dominant polycystic kidney disease (ADPKD). The variability can not be fully explained by the genetic heterogeneity of the disease. We examined the influence of the ACE I/D polymorphism, adducin Trp460Gly polymorphism and the association of both polymorphisms on the progression of ADPKD towards end-stage renal failure (ESRF). METHODS: 320...

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Share to Calmodulin-Binding Proteins
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Kidney Failure, Chronic

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Share to Polycystic Kidney, Autosomal Dominant

Share to Polymorphism, Genetic

Source

Identifiers

PMID: 12697976
DOI: 10.1159/000069768

Genes

ACE

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