Article
Human epidermal growth factor receptor 2/neu as a novel therapeutic target in sinonasal undifferentiated carcinoma.
Head & neck - 1 Apr 2016
Takahashi Yoko, Lee Junegoo, Pickering Curtis, Bell Diana, Jiffar Tilahun W, Myers Jeffrey N, Hanna Ehab Y, Kupferman Michael E
Abstract excerpt
BACKGROUND: Sinonasal undifferentiated carcinoma (SNUC) is a rare and aggressive cancer. Despite multimodal therapy, the prognosis in SNUC remains poor, and new therapies are needed. Thus, the purpose of this study was to explore potential therapeutic targets in SNUC. METHODS: Using the human-derived SNUC MDA8788-6 cell line, we performed whole genome single nucleotide polymorphism (SNP) analysis to identify copy...
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