Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Receptor tyrosine kinases in sinonasal undifferentiated carcinomas--evaluation for EGFR, c-KIT, and HER2/neu expression.

Head & neck - 1 Jul 2009

Chernock Rebecca D, Perry Arie, Pfeifer John D, Holden Joseph A, Lewis James S

Abstract excerpt

BACKGROUND: Our objective was to identify the expression of epidermal growth factor receptor (EGFR), c-KIT (CD117), and HER2/neu in sinonasal undifferentiated carcinoma (SNUC). METHODS: Immunohistochemistry for c-KIT (CD117), EGFR, and HER2/neu was performed on paraffin-embedded tissue from SNUC cases. A search for activating mutations in c-kit exons 9, 11, 13, and 17 or gene amplification was undertaken by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Aged, 80 and over
Share to Carcinoma

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cohort Studies

Share to In Situ Hybridization, Fluorescence

Share to Paranasal Sinus Neoplasms

Share to Polymerase Chain Reaction

Share to Receptor Protein-Tyrosine Kinases

Source

Identifiers

PMID: 19283847
DOI: 10.1002/hed.21061

Genes

KIT
EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Receptor tyrosine kinases in sinonasal undifferentiated carcinomas--evaluation for EGFR, c-KIT, and HER2/neu expression.PMID 19283847Read ↗

Molecular profiling of sinonasal undifferentiated carcinoma.Semantic proximity Read ↗

Human epidermal growth factor receptor 2/neu as a novel therapeutic target in sinonasal undifferentiated carcinoma.Semantic proximity Read ↗

Clinical and molecular evidence for c-kit receptor as a therapeutic target in neuroblastic tumors.Semantic proximity Read ↗

Gene amplification and protein overexpression of EGFR and ERBB2 in sinonasal squamous cell carcinoma.Semantic proximity Read ↗

Establishment and characterization of novel cell lines from sinonasal undifferentiated carcinoma.Semantic proximity Read ↗

Merkel cell carcinoma: evaluation of KIT (CD117) expression and failure to demonstrate activating mutations in the C-KIT proto-oncogene - implications for treatment with imatinib mesylate.Semantic proximity Read ↗

Merkel cell carcinoma: correlation of KIT expression with survival and evaluation of KIT gene mutational statusSemantic proximity Read ↗

KIT activation in uterine cervix adenosquamous carcinomas by KIT/SCF autocrine/paracrine stimulation loops.Semantic proximity Read ↗

Expression and mutational status of c-kit in small-cell lung cancer: prognostic relevance.Semantic proximity Read ↗

C-kit overexpression is not associated with KIT gene mutations in chromophobe renal cell carcinoma or renal oncocytoma.Semantic proximity Read ↗

C-KIT overexpression and mutation in nasopharyngeal carcinoma cell lines and reactivity of Imatinib on these cell lines.Semantic proximity Read ↗

KIT protein expression and analysis of c-kit gene mutation in adenoid cystic carcinoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.